Since the new coronavirus was first discovered, there have been multiple rounds of mutation, so will nucleic acid detection as the “gold standard” lose its effectiveness due to mutation? According to the Beijing News, Liu Xiaofeng, deputy director of the Beijing Center for Disease Control and Prevention, responded at a press conference on epidemic prevention and control held on May 19. He said that at present, nucleic acid detection of new coronary pneumonia is the most effective and accurate virus detection method, and it is also an important means to deal with epidemic prevention and control. In terms of technology, although the virus is constantly mutating, my country’s new coronavirus nucleic acid detection reagents are designed for conservative sequences with fewer new coronavirus mutation sites. Therefore, domestic nucleic acid detection reagents are not affected by virus mutation and are sensitive and reliable. . As for antigen detection, it is mainly used as a supplementary method to screen high-risk groups to improve the ability of early detection. He introduced that antigen detection does not have the PCR technology of nucleic acid detection to amplify the virus signal, does not have the process of signal amplification, and is less sensitive than nucleic acid detection. It is worth mentioning that on the program “I Am a Great Doctor” on Beijing Satellite TV a few days ago, a chief physician of the Department of Infectious Diseases said that drinking water or eating before the nucleic acid test will dilute the virus attached to the pharynx, especially drinking hot water, will suppress the virus.
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