The world’s longest follow-up of early new crown patients in Wuhan still has symptoms after 2 years: this is the most common

According to Health Times, on May 12,“The Lancet Respiratory Medicine” published a two-year follow-up study on discharge of new coronary pneumonia in Wuhan. The results showed that early-stage patients with COVID-19 still had symptoms 2 years later. Of these, fatigue or muscle weakness are the most common symptoms.

It is understood that the research was jointly completed by the team of Professor Cao Bin of China-Japan Friendship Hospital and Professor Wang Jianwei of Peking Union Medical College.This is also the longest follow-up study of COVID-19 patients to date.

The study followed up 1,192 patients hospitalized with COVID-19 in Wuhan, China from January 7 to May 29, 2020, and followed the patients 6 months, 12 months, and two years after discharge.

Assessments included a 6-minute walk test, laboratory testing, and a questionnaire that included symptoms, mental health, health-related quality of life, return to work, and discharge health care utilization.

research shows,Compared with the general population, people who have recovered from Covid-19 tend to have poorer health 2 years after their initial infection, and about half of those who have recovered from Covid-19 still have long-term effects of Covid-19, such as fatigue and difficulty sleeping, 2 years after discharge.

The median age of subjects at hospital discharge was 57 years, and 54% were men (641). Six months after initial onset, 68% of patients reported at least one long-term symptom, which dropped to 55% 2 years after infection.

Fatigue or muscle weakness was the most common symptom, decreasing from 52% at 6-month follow-up to 30% at 2-year follow-up.

In addition, at 6 months of follow-up, 26% of discharged patients had dyspnea, which was significantly reduced to 14% at 2 years; anxiety or depressive symptoms decreased from 23% at 6 months to 2% 12% year-on-year.

According to the study, there are fluctuations or recurrences of fatigue after the new crown, but the mechanism is not clear, and it is likely to be due to the combined effect of central, peripheral and psychological factors.

Previous studies on SARS (atypical pneumonia) and MERS (Middle East Respiratory Syndrome) described abnormal pulmonary fibrosis during convalescence, and this sign can also be observed months or even years after infection with the new crown,suggest that pulmonary fibrosis may be a long-term effect of COVID-19.

Encouragingly, regardless of initial disease severity, patients’ physical and mental health improved over time, with nearly 90 percent returning to their previous jobs after two years.

Hashtags: Biomedical Novel Coronavirus Research